Preexisting Cognitive Impairment Is Associated with Postoperative Cognitive Dysfunction after Hip Joint Replacement Surgery

B Silbert; L Evered; DA Scott; S McMahon; P Choong; D Ames; P Maruff; K Jamrozik

Journal article

Preexisting Cognitive Impairment Is Associated with Postoperative Cognitive Dysfunction after Hip Joint Replacement Surgery

B Silbert, L Evered, DA Scott, S McMahon, P Choong, D Ames, P Maruff, K Jamrozik

Anesthesiology | Published : 2015

DOI: 10.1097/ALN.0000000000000671

Abstract

Background: This study investigated the prevalence of cognitive impairment in elderly noncardiac surgery patients and any association between preoperative cognitive impairment and postoperative cognitive dysfunction (POCD). Additionally, the incidence of cognitive decline at 12 months after surgery was identified. Methods: Three hundred patients for hip joint replacement and 51 nonsurgical controls aged 60 yr or older were studied in a prospective observational clinical trial. All study participants and controls completed a battery of eight neuropsychological tests before surgery and at 7 days, 3 months, and 12 months afterwards. Preoperative cognitive status was assessed using preexisting c..

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University of Melbourne Researchers

Brendan Silbert Author

Lis Evered Author

David Ames Author

Paul Maruff Author

Related Projects (1)

How anaesthesia effects mental function

It is known that about 10% of patients over the age of 55 have difficulty with cognition and thinking 3 months after surgery and anaesthesia..

Grants

Awarded by Australian National Health and Medical Research Council, Canberra, Australian Capital Territory, Australia

Funding Acknowledgements

Support was provided by the Australian National Health and Medical Research Council, Canberra, Australian Capital Territory, Australia (project grant 454440).